胎儿生长受限与小于胎龄孕妇心输出量和全身血管阻力的差异研究Study on differences of cardiac output and systemic vascular resistance between fetal growth restriction and small for gestational age in pregnant women
倪俊红;陈程;
摘要(Abstract):
目的比较妊娠合并胎儿生长受限(fetal growth restriction,FGR)和妊娠合并小于胎龄(small for gestational age,SGA)孕妇心输出量(cardiac output, CO)和全身血管阻力(Systemic vascular resistance,SVR)的差异。方法选择2016年5月-2019年7月在中国人民解放军联勤保障部队第901医院孕检和分娩的孕妇,102例诊断为FGR的孕妇(FGR组),64例诊断为单纯SGA的孕妇(SGA组),401正常孕妇(对照组),均为孕28周以上,进行血流动力学进行评估,比较3组产妇的CO和SVR的组间差异,并分析这些指标与新生儿出生体质量的相关性。结果 FGR组的心率(heart rate, HR)和CO低于SGA组,而平均动脉压(mean arterial pressure, MAP)、SVR和子宫动脉搏动指数高于SGA组,差异均具有统计学意义(P<0.05)。与正常组比较,SGA组CO和SVR差异无统计学意义(P>0.05)。新生儿出生体质量百分位数与CO呈正相关,与SVR和子宫动脉搏动指数呈负相关(P<0.05)。结论合并FGR的孕妇,其母体血流动力学特征表现为SVR增加,CO减少。单纯SGA胎儿产妇具有基本正常的CO和SVR。
关键词(KeyWords): 胎儿生长受限;小于胎龄儿;血流动力学;妊娠
基金项目(Foundation): 安徽省科技计划项目(1501041159)
作者(Author): 倪俊红;陈程;
Email:
DOI:
参考文献(References):
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