赵倩,徐锐,杨毅宁,马依彤,李晓梅,向阳,陈邦党,刘芬

• 1:新疆医科大学第一附属医院心脏中心

摘要(Abstract)：

目的探讨平均血小板体积(mean platelet volume,MPV)在诊断中青年急性心肌梗死及预测冠状动脉病变严重程度中的作用。方法选择2013年8月-2013年12月在新疆医科大学第一附属医院住院的中青年急性心肌梗死患者(年龄<60岁)131例为病例组,根据冠状动脉造影结果对病例组进行冠状动脉狭窄程度积分(Gensini积分)评价,其中高于Gensini积分中位数(P50=40分)有67例,低于P50(<40分)有64例。选择152例同时期本院健康体检者为对照组。比较病例组与对照组、病例组中Gensini积分高于P50的患者与Gensini积分低于P50患者的MPV,多元线性回归分析MPV与Gensini积分的相关性。结果病例组MPV水平为(10.27±1.27)fL,高于对照组的(9.60±1.50)fL(P<0.05)。病例组中Gensini积分高于P50患者的MPV水平为(10.51±1.32)fL,高于Gensini积分低于P50患者的(10.02±1.17)fL,(P<0.05)。多元线性回归显示,MPV与Gensini具有相关性(P<0.05)。结论 MPV在诊断中青年急性心肌梗死及预测冠状动脉病变严重程度方面具有一定的价值。

关键词(KeyWords)： 急性心肌梗死;中青年;MPV;冠状动脉病变程度

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金(81060025);; 教育部新世纪优秀人才支撑计划(NCET-11-1074)

作者(Author): 赵倩,徐锐,杨毅宁,马依彤,李晓梅,向阳,陈邦党,刘芬

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