新疆医科大学学报

目的探究养血祛风汤联合耳穴压豆治疗血虚风燥型特应性皮炎临床价值。方法选择桂林市中医医院皮肤科2019年1月-2020年11月收治的98例特应性皮炎患者为研究对象,采用随机数字表法分为对照组与试验组,每组49例。对照组给予常规西医治疗,试验组在对照组基础上给予养血祛风汤+耳穴压豆治疗,两组均治疗4周。对比两组患者临床疗效、安全性及治疗前后病情相关评分(SCORAD)、血清IgE及生活质量评分(DLQI)变化,随访3个月,统计对比两组复发率。结果与对照组比较,试验组患者临床总有效率升高,患者SCORAD评分、DLQI评分和血清IgE水平均降低,差异有统计学意义(P<0.05)。治疗期间两组患者血尿常规、肝肾功能均未见明显异常。对两组患者随访3个月,与试验组比较,对照组患者复发率降低,差异有统计学意义(χ²=4.166,P=0.041)。结论养血祛风汤联合耳穴压豆治疗血虚风燥型特应性皮炎安全有效,复发率低。

Objective To explore the clinical value of Yangxue Qufeng decoction combined with auricular point pressing beans in the treatment of atopic dermatitis of blood deficiency and wind dryness type. Methods A total of 98 patients with atopic dermatitis in Department of Dermatology, Guilin Hospital of traditional Chinese medicine from January 2019 to November 2020 were selected as the research objects and randomly divided into control group and experimental group with 49 cases in each group. The control group was treated with conventional western medicine, while the experimental group was treated with Yangxue Qufeng Decoction + auricular point pressing beans on the basis of the control group. Both groups were treated for 4 weeks. The clinical efficacy, safety and changes of SCORAD, serum IgE and DLQI before and after the treatment were compared between the two groups. The recurrence rates of the two groups were compared after 3 months of follow-up. Results Compared with the control group, the clinical total effective rate of the experimental group was higher, and the SCORAD score, DLQI score and serum IgE level of the patients were lower(P < 0.05). During the treatment, the blood and urine routine, liver and kidney function of the two groups were not significantly abnormal. After 3 months follow-up, compared with the experimental group, the recurrence rate of the control group was lower(χ²=4.166, P=0.041). Conclusion Yangxue Qufeng decoction combined with auricular point pressing beans is safe and effective in the treatment of atopic dermatitis of blood deficiency and wind dryness type with low recurrence rate.