新疆医科大学学报

目的分析研究新疆阿克陶县干眼病患者患病率及相关因素。方法以新疆阿克陶县1200例健康人作为研究组对象,采用多阶段抽样方法,通过计基线资料调查问卷调查纳入对象基线资料情况,为全部入组者行相关眼部检查,根据眼部检查结果判定干眼发生情况,根据性别、年龄、工作性质等分为不同亚组,分析比较不用亚组的干眼患病率,以及性别、年龄、工作性质等对泪膜稳定性的影响。结果 1 200例健康人经各眼部检查检出干眼者408例,检出率为34.00%;女性干眼检出率高于男性;45～65岁年龄亚组检出率高于其他两个年龄亚组、户外组检出率高于室内组、高强度用眼组检出率高于低强度用眼组,异均有统计学意义(P<0.05)。经非条件多项Logistic回归分析检验结果显示:女性、年龄45～65岁、日常生活习惯多在户外、工作性质多为高强度用眼均是新疆阿克陶县健康人群干眼症的影响因素(OR>1,P<0.05)。结论新疆阿克陶县健康人干眼病受性别、年龄、日常生活习惯、工作性质等因素影响,该地区降水量少、昼夜温差大等气候特点导致的干旱生活环境可能是导致户外工作时间长、高强度用眼健康人群发生干眼的主要原因。

Objective To observe the prevalence rate of dry eye in Akto of Xinjiang and analyze the possible influencing factors. Methods A multi-stage sampling method was used to determine 1 200 healthy people in Akto county of Xinjiang as the research group, and the baseline data questionnaire was designed to investigate the baseline data of the subjects. The relevant eye examinations were conducted for all the subjects, and the occurrence of dry eye was determined according to the results of the eye examination. 1 200 cases were divided into different subgroups according to gender, age, and nature of work. The prevalence rate of dry eye in subgroups was compared, and the effects of gender, age, and nature of work on tear film stability were examined by multiple non-conditional Logistic regression analysis. Results A total of 408 cases of dry eye were detected by various eye examinations in all 1 200 healthy people, and the detection rate was 34.00%; the detection rate of dry eye in female was higher than that in male and 45-65 years old. The detection rate was higher than that in the other two age subgroups, the detection rate in outdoor group was higher than that in indoor group, the detection rate in high-intensity eye group was higher than that in low-intensity eye group with statistical significance. The results of non-conditional multiple Logistic regression analysis showed that the female, aged from 45 to 65, more outdoor daily life, and more high-intensity eye work were influencing factors for dry eye of healthy people in Akto county of Xinjiang(OR>1, P<0.05). Conclusion The dry eye of healthy people in Xinjiang is affected by factors such as gender, age, daily habits, and the nature of work. The dry living environment caused by climatic characteristics such as low rainfall and large temperature difference between day and night may lead to dry eye in healthy people with long outdoor working hours and high-intensity eye.