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目的探讨静脉滴注头孢哌酮钠后饮酒致双硫仑样反应的原因、救护及预防要点。方法对2例静脉滴注头孢哌酮纳后饮酒致双硫仑样反应的临床表现、治疗及救护进行回顾性分析,临床在执行治疗时,询问过敏史外,并且特别注意询问饮酒史。结果 2例患者经积极治疗及护理,均恢复良好,2h后症状缓解,1例患者遗留全身乏力、厌食等症状,持续2d后缓解。结论使用头孢哌酮钠等抗生素时应禁止饮酒,避免发生双硫仑样反应,确保临床用药安全。
Abstract:Objective To investigate cause,rescue and prevention points of disulfiram-like reaction caused by drinking after intravenous infusion of cefoperazone sodium.Methods Conducted a retrospective analysis of clinical manifestations,treatment and rescue on two cases of patients with disulfiram-like reaction caused by intravenous infusion of cefoperazone sodium.We should ask drinking history in addition to allergic history when execute clinical treatment.Results The symptom remitted after two hours by active treatment and care.But one patient left over symptom such as weak,anorexia,remitted after two days.Conclusion Using of antibiotics like cefoperazone sodium should prohibit drinking alcohol for avoiding disulfiram-like reaction,ensure the safety of the usage of clinical drugs.
[1]慈书平,赵宁志.药源性双硫仑反应处理及预防[J].中国药物应用与监测,2007,42(5):53-55.
[2]张红,苏德森.戒酒药双硫仑[J].中国药物杂志,2000,9(11):747.
[3]张彦敏,王力.护理程序在双硫仑样反应急救中应用[J].护理实践与研究,2006,6(3):48-49.
[4]韩敏,郭春萍.停用头孢哌酮后饮酒致双硫仑样反应1例报道[J].吉林大学学报,2007,5(33):840-841.
[5]王玉华.第三代头孢菌素类药物的“双硫仑样”反应观察及处理对策[J].药物与临床,2008,46(13):103.
[6]苏静,周华晟.应用药物后饮酒致双硫仑反应63例临床分析[J].山东医药,2008,(31):41.
[7]吴美丽,吴泉英.1500例致双硫仑反应的统计与分析[J].海峡药学,2009,2(21):127-128.
基本信息:
中图分类号:R595.3
引用信息:
[1]崔世红,董树婉.静脉滴注头孢哌酮钠后饮酒致双硫仑样反应的原因分析及救护[J].新疆医科大学学报,2013,36(01):128-130.
2013-01-15
2013-01-15