| 204 | 5 | 29 |
| 下载次数 | 被引频次 | 阅读次数 |
目的探讨高分辨磁共振血管壁成像技术对高血压患者豆纹动脉(Lenticulostriate artery,LSA)数量及深度的特征分析。方法以2018年5月-2019年4月新疆医科大学第二附属医院影像中心收治的76名高血压患者为研究对象,根据中国老年高血压管理指南2019血压等级分为Ⅰ级(25例)、Ⅱ级(27例)、Ⅲ级(24例)高血压组,另取27名健康志愿者为对照组。对所有受试者行高分辨磁共振血管壁成像(High Resolution Magnetic Resonance Imaging,HR-MRI)3D-T1WI-VISTA序列成像,受试者双侧豆纹动脉高分辨血管成像数据传至后处理工作站,应用Philips Intellispace portal软件对的血管数量及深度进行统计,采用SPSS 22.0软件对4组受试者双侧豆纹动脉的深度及数目进行统计学分析。结果与对照组比较,各级高血压组组间一般资料差异均无统计学意义(P>0.05)。与对照组比较,Ⅰ级高血压组患者双侧豆纹动脉深度和数目差异无统计学意义(P>0.05);Ⅱ、Ⅲ级高血压组患者双侧豆纹动脉的深度和数目降低,差异有统计学意义(P<0.01)。结论高分辨磁共振血管壁成像对豆纹动脉血管特征分析具有临床价值,Ⅱ、Ⅲ级高血压患者的双侧豆纹动脉的数量及深度低于正常人群。
Abstract：Objective To explore the value of HR-MRI in the study of the number and depth of lenticular artery in patients with hypertension. Methods A total of 76 hypertensive patients admitted to the Imaging Center of the Second Affiliated Hospital of Xinjiang Medical University from May 2018 to April 2019 were studied. According to the blood pressure level grades in the Chinese Guidelines for the Management of Senile Hypertension in 2019, they were divided into the first grade(25 cases), the second grade(27 cases) and the third grade(24 cases) hypertension groups. Twenty-seven healthy volunteers were selected as the control group. High Resolution Magnetic Resonance Imaging(HR-MRI) and 3 D-T1 WI-VISTA sequence imaging were performed in all subjects. The number and depth of blood vessels were analyzed by Philips Intellispace portal software at the data transmitter workstation of high resolution arteriography of lenticulostriate arteries in all subjects. Results Compared with the control group, there was no significant difference in the general data between the hypertension groups at all levels(P>0.05). Compared with the control group, there was no significant difference in the depth and number of bilateral lenticular arteries between the first grade hypertension group and the control group(P>0.05). The depth and number of bilateral striated lenticular arteries in patients with the second-grade and the third-grade hypertension were decreased, and the difference were statistically significant(P<0.01). Conclusion HR-MRI is of clinical value in the analysis of arterial characteristics of lenticulostriate artery. The number and depth of bilateral lenticulostriate arteries in patients with the second grade and the third grade hypertension are lower than those in normal subjects.
[1] 李静,范利,华琦,等.中国老年高血压管理指南2019[J].中国心血管杂志,2019,24(1):1-23.
[2] 茅翼亭,方堃,董强,等.缺血性脑卒中的病因分型与危险因素[J].中华脑血管病杂志,2009,3(2):68-75.
[3] 李明春,刘振华.缺血性脑卒中患者脑动脉狭窄的好发部位及危险因素的研究[J].中国当代医药,2012,19(11):152-154.
[4] 于善花,庄爱霞,王阳,等.豆纹动脉区分支动脉粥样硬化病和腔隙性脑梗死早期神经恶化的临床研究[J].东南大学学报(医学版),2017,36(5):822-827.
[5] 赵晓红.急性脑卒中内脏并发症26例临床分析[J].川北医学院学报,2011,16(3):71-73.
[6] 杨心怡,郝俊杰,李刚.缺血性脑卒中危险因素研究进展[J].中华卫生应急电子杂志,2019,5(1):57-60.
[7] ZHANG Z,FAN Z,KONG Q,et al.Visualization of the lenticulostriate arteries at 3T using black-bloodT1-weighted intracranial vessel wall imaging:comparison with 7T TOF-MRA[J].Eur Radiol,2019,29(3):1452-1459.
[8] 刘影.正常成人大脑中动脉的MRA研究[D].延吉:延边大学,2014.
[9] 陈娜.PAK1在豆纹动脉血管内皮损伤及高血压脑出血中的作用[D].重庆:重庆大学,2016.
[10] 李小飞.豆纹动脉区域流体动力学的分析及出血易发点的预测[D].重庆:重庆大学,2017.
[11] 李成武.高血压性视网膜病变与脑卒中相关性的临床研究[D].北京:中国中医科学院,2016.
[12] 张鑫月,贾振华,常丽萍.高血压微血管发病机制研究进展[J].中华高血压杂志,2014,22(8):718-722.
[13] DERVENIS N,COLEMAN A L,HARRIS A,et al.Factors associated with retinal vessel diameters in an elderly population:the thessaloniki eye study[J].Invest Ophthalmol Vis Sci,2019,60(6):2208-2217.
[14] 高涛.血压对缺血性卒中脑血流动力学、神经功能缺损的影响[D].郑州:河南科技大学,2015.
[15] 张凌云,付旷.高血压脑病发病机制及相关MRI表现[J].医学影像学杂志,2014,24(4):603-606.
[16] 赵敏.代谢综合征病人颅内动脉血管病变特点的分析[J].中西医结合心脑血管病杂志,2016,14(4):431-432.
[17] 赵世亮.基于脑血管造影结果分析脑血管狭窄与高血压病、糖尿病的相关性[D].南宁:广西中医药大学,2016.
基本信息:
中图分类号:R445.2;R544.1
引用信息:
[1]林威龙,贾琳,王云玲,等.高分辨磁共振血管壁成像对高血压患者豆纹动脉血管特征分析的应用研究[J].新疆医科大学学报,2019,42(11):1430-1432+1436.
基金信息:
国家自然科学基金(81860301)
2019-05-10
2019
2019-07-12
2019
1
2019-11-12
2019-11-12