新疆医科大学学报

目的探讨新疆新源县哈萨克族居民膳食营养素摄入状况及血清叶酸与哈萨克族食管癌的关系。方法采用24 h膳食回顾法调查234名哈萨克族居民(食管癌组84例,对照组150例)各营养素的摄入情况,将结果与中国居民膳食营养素参考摄入量(DRIs)进行比较分析。全自动化学发光免疫法测定血清叶酸水平。结果食管癌组、对照组能量、蛋白质、钙、铁、钠、维生素A、硫胺素、核黄素、叶酸的摄入量分别达到DRIs的85.58%和122.83%、122.65%和169.82%、75.50%和95.78%、166.43%和226.47%、194.61%和226.06%、64.61%和91.28%、67.38%和89.57%、87.13%和100.44%、32.58%和7.53%。血清叶酸高组中食管癌组与对照组比较,差异有统计学意义(P<0.05),血清叶酸高组人群患食管癌的风险是最低组人群的0.16倍。结论哈萨克族食管癌患者铁和钠的摄入量偏高;能量、钙、维生素A、硫胺素、核黄素、维生素C的摄入量不足;叶酸的摄入量偏低;血清叶酸水平低时患食管癌的风险高。

Objective To research the relationship between the nutrition status,folic acid levels and esophageal cancer of Kazak people in Xinyuan Xinjian.Methods Among 234 Kazak residents,there were 84 cases of patients with esophageal cancer(study group) and 150 cases of the general population(control group).Their intake status of nutrition were measured by 24 hours review method,then analyzed these data by comparing them with the Dietary Reference Intakes(DRIs).Automated chemiluminescence immunoassay were uaed to determine folic acid levels.Results Case group and control group of energy,protein,calcium,iron,sodium,vitamin A,thiamine,riboflavin,folic acid intake in the proportion of DRIs were 85.58% and 122.83%,122.65% and 169.82%,75.50% and 95.78%,166.43% and 226.47%,194.61% and 226.06%,64.61% and 91.28%,67.38% and 89.57%,87.13% and 100.44%,32.58% and 7.53% respectively.There were statistical significances between the high levels group and control group(P<0.05).The risk of the high levels group was 0.16 times than the minimum population group.Conclusion Among Kazak esophageal cancer residents,the quantity of iron and sodium is higher than DRIs.Tthe quantity of energy,calcium,vitamin A,thiamine,riboflavin,vitamin C is deficient.The quantity of folic acid is a little lower than DRIs.When the folic acid level is low,the risk of developing esophageal cancer will increase.